Analytical Components International (ACI) Launches High-Performance Seals Compatible with Major HPLC Pumps 

Stoughton, MA, May 28, 2026 – Analytical Components International (ACI), a leading manufacturer of precision components for analytical instrumentation and innovator in the hard materials industry, specializing in synthetic sapphire and precision ceramic components for the industrial, medical and life science industries, has today announced a new line of high-performance seals compatible with major HPLC pumps.

For decades, the ACI team has set the industry standard for the hard material components of the HPLC pump, including sapphire and ceramic pistons. By launching this dedicated line of high-performance seals, specifically designed for use with Agilent® HPLC pumps and Waters® HPLC pumps (designed and manufactured to meet or exceed OEM performance), ACI now offers a high-performance aftermarket seal solution for the Piston-Seal Interface. This validated system approach reduces the risk of premature seal failure and ensures pulse-free flow at pressures exceeding 15,000 psi.

The success of an HPLC pump depends on the precision fit between the piston and the seal. By engineering both components, ACI eliminates the compatibility gaps that often occur when mixing third-party pistons and seals. ACI pistons are polished to industry leading surface finishes, and seals are designed to minimize seal degradation. Materials are optimized for each system: graphite-filled PTFE for aftermarket Agilent® pumps, and reinforced UHMW-PE for aftermarket Waters® ACQUITY® pumps, providing reliable, high-pressure performance and extended maintenance intervals.

These seals are engineered for use with widely used OEM HPLC and UHPLC pump part numbers, ensuring direct replacement or performance upgrades for the original systems:

• Seals compatible with Agilent® 1100/1200/1260 pumps (cross-reference OEM P/N 5063-6589, 0905-1420)
• Seals compatible with Waters® Alliance pumps (cross-reference OEM P/N WAT271018, WAT270938, WAT271017, WAT270939, WAT270940)
• Seals compatible with Waters® ACQUITY® pumps (cross-reference OEM P/N 700002598, 700002599)

ACI part numbers corresponding to these OEM references are available for ordering.

“With this launch, ACI closes the loop on the HPLC pump head,” said Isabelle Darcy, Operations Management at ACI. “By combining our world-class sapphire pistons with precision-engineered seals, we are providing high-performance aftermarket seals to support reliable operation in existing HPLC systems. This isn’t just a new product line; it is a commitment to ensuring reliable, high-performance operation throughout the analytical workflow.”

To learn more about ACI’s HPLC and UHPLC seals, visit: https://analyticalcomp.com/seals/

Agilent® and Waters® are registered trademarks of their respective owners. ACQUITY® is a registered trademark of Waters Corporation. Analytical Components International (ACI) is not affiliated with, or endorsed by, these companies. All OEM part numbers are provided solely for cross-reference purposes. Reference to these trademarks is for informational purposes only and does not imply sponsorship, affiliation, or endorsement.

About Analytical Components International

Analytical Components International (ACI) brings more than 50 years of experience in the hard materials industry, specializing in custom sapphire and precision ceramic components for OEMs in the industrial, medical and life science industries. Additionally, ACI is a manufacturer of life science components & assemblies, selling fluidic connections and tubing for the Analytical Instrumentation, Biotechnology and Invitro Diagnostic markets. With a focus on quality, innovation, and customer service, ACI provides a wide range of products and services to meet the needs of researchers, scientists, and engineers worldwide. The company is headquartered in Massachusetts, USA. To learn more, visit analyticalcomp.com or contact us at [email protected] or +1.781.436.2780.